Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions

Abstract Background Persistent high risk HPV infection can lead to cervical cancer, the second most common malignant tumor in women worldwide.NK cells play a crucial role against tumors and virus-infected cells through a fine balance between activating and inhibitory receptors.Expression of triggering receptors NKp30, NKp44, NKp46 and NKG2D on NK c

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